Valproic acid, as an inhibitor of hepatic microsomal enzymes, exerts its detrimental effects on bone health through several mechanisms including induction of
Valproic acid (VPA) is one antiepileptic drug that is effective in treating generalized and partial seizures, primarily absence seizures
Metabolic evidence of vitamin B12 deficiency, including high homocysteine and methylmalonic acid and low holotranscobalamin, is more pronounced in older
Interactions
Valproic acid-induced encephalopathy mainly manifests as acute or subacute encephalopathy and has been associated with hyperammonemia, L-carnitine deficiency
Per the Harvard School Of Public Health, symptoms of Vitamin A toxicity include: Vision changes such as
Vitamin A deficiency exacerbates invasive non-typhoidal Salmonella infection in mice, revealing a restrictive role for SLC11A1 in neutrophils
This prospective monocenter study aimed at testing the hypothesis that AED treatment is associated with folate and vitamin B12 serum levels in a large population
There was a significant difference between case and control groups
To assess the effect of monotherapy with Carbamazepine (CBZ) and Sodium valproate (VPA) on serum 25-OH Vitamin D levels in children with epilepsy compared to controls
Abnormal gait in children, often noticed by parents or caregivers is a common presentation in orthopedic outpatient departments and requires a comprehensive work-up
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling)
Although it usually results in mild central nervous system depression, serious toxicity and even fatal cases have been reported
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Alcohol can increase the nervous system side effects of valproic acid such as dizziness, drowsiness, and difficulty concentrating
Valproic acid (VPA), or sodium valproate, is a common antiepileptic drug that is widely used for generalized or focal seizures
Valproic acid (VPA), a branched short-chain fatty acid, is widely used as an antiepileptic drug and a mood stabilizer
We established rat models with different VA levels based on the valproic acid-induced autism model
v) High fever and convulsion
6 Deficiency can result from a lack of IF or hydrochloric acid in the stomach that is required to liberate vitamin B 12 from its bound state Valproic Acid (Depakene®) – anticonvulsant used for migraine headache prevention
However, the relationship between VA deficiency (VAD) and ASD with GI comorbidities is still unclear