Background: Methylphenidate, modafinil, and amantadine are commonly prescribed medications for alleviating fatigue in multiple sclerosis; however, the evidence supporting their efficacy is sparse and conflicting
Side effects are rare
The most common starting dose was 100 mg twice daily for both amantadine (86%) and modafinil (54%)
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difficulty urinating
May cause orthostatic hypotension and increase the risk of falls
Use low dose for restless leg syndrome
doi: 10
In Canada - Call your doctor for medical advice about side effects
Efficacy and safety of amantadine for the treatment of fatigue in multiple sclerosis: a systematic review and meta Despite its prevalence, limited research has explored effective treatments for post-COVID-19 fatigue
Side effects that you should report to your doctor or health care professional as soon as possible: allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
Parkinson Disease* / drug therapy