Xeloda navelbine breast cancer

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  • Background: Breast cancer has an unacceptably high recurrence rate
  • A new oral formulation of vinorelbine has been introduced
  • Introduction: capecitabine or vinorelbine
  • Metastatic means the cancer has spread to other parts of the body
  • Onkologie 26:578-580, 2003
  • Diarrhea
  • 2016;12(3):373-87 The purpose of this study is to find the highest dose of capecitabine and oral navelbine that can be given without causing severe side effects, and to determine the safety, tolerability, and effects (good and bad) of capecitabine given with oral navelbine to patients with advanced breast cancer

    SEOUL, Korea Use of capecitabine (Xeloda) plus vinorelbine (Navelbine) is effective in metastatic breast cancer patients previously treated with anthracycline and taxane drugs, according to preliminary data from a phase II study

    12-13

    Intravenous and oral combination of vinorelbine (VRL) and capecitabine were shown to be feasible and effective in first-line MBC

    Its brand name is Navelbine

    A multicenter phase II trial assessed the activity, safety and pharmacokinetic profile of oral navelbine in ABC

    Vinorelbine is an active drug in AMBC, particularly in breast, lymph nodes and skin/soft tissue sites, with an excellent tolerance

    Background: Few data are available on the benefit of metronomic cyclophosphamide, capecitabine, and vinorelbine as first-line therapy in patients with metastatic triple-negative breast cancer

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